Activation of human monocytes/macrophages by hypo-osmotic shock
نویسندگان
چکیده
منابع مشابه
Haemolytic effects of hypo-osmotic salt solutions on human erythrocytes.
BACKGROUND While it is well known that hypotonic solutions of sodium chloride induce hemolysis, the effects of other salt solutions on human erythrocytes have not been well documented. OBJECTIVE The study is to compare the effects of other salt solutions on human red cells. METHODS Iso-osmotic and hypo-osmotic solutions of various salts were prepared after taking into account their molecula...
متن کاملActivation of heat shock factor 1 by hyperosmotic or hypo-osmotic stress is drastically attenuated in normal human fibroblasts during senescence.
We have previously reported that osmotic stress prominently induces the DNA binding activity of the heat shock transcription factor 1 (HSF1). In the present study, we examined the effects of medium osmolarity on both the activation of HSF1 and the programmed cell death in normal human fibroblasts during cellular senescence. The activation of HSF1 occurred rapidly in presenescent (early passage)...
متن کاملEstablishment of an optimal hypo-osmotic swelling test by examining single spermatozoa in four different hypo-osmotic solutions.
In order to find an optimal hypo-osmotic swelling test (HOST) and to identify viable sperm cells from patients with asthenozoospermia for intracytoplasmic sperm injection (ICSI), we tested single motile and non-motile spermatozoa in four hypo-osmotic solutions by micromanipulation. The four solutions were: A, H2O; B, 50 mOsm NaCl; C, 150 mOsm NaCl and D, 150 mOsm sodium citrate and fructose. Eo...
متن کاملOccurrence of osmotic shock in human spermajozoa:
Objective: Mammalian spermatozoa swell under hypotonic conditions. The exposure of spermatozoa to isotonic conditions after exposure to hypertonic conditions during cryopreservation results in the occurrence of osmotic shock, which is characterized by coiling of the distal end of the sperm tail. The objective of this study was to assess the effects of osmotic shock (% sperm coiling) on human cr...
متن کاملhypo-osmotic stress in mammalian cells
Osmoregulation is important to living organisms for survival in responding to environmental changes ofwater and ionic strength. We demonstrated here for the first time that exposure of HeLa cells to a hypotonic medium (30% growth medium and 700% water) prominently induced the binding activity of the heat shock transcription factor (HSF). Pretreatment of cells with cycloheximide did not inhibit ...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2001
ISSN: 0009-9104
DOI: 10.1046/j.1365-2249.2001.01496.x